Dementia is one of the most feared illnesses of older people. It is also one of the most expensive illnesses, as affected individuals may require care for many years, impacting them, their family, and society at large. The potential to prevent dementia is very high, with around 45% of the risk being accounted for by fourteen potentially modifiable risk factors. However, risks are more prevalent in underserved people, who are more likely to have dementia and at an earlier age. This panel will discuss how evidence was evaluated to decide on which putative risk factors to include in the Commission’s model, taking into account prevalence, relative risk, and communality.
Action to tackle these risk factors begins in early life and continues throughout life and is at the level of policy as well as the individual. There is evidence of the effectiveness of reducing such factors, even in individuals with high genetic risk for dementia. Early and continuous Intervention should lead to a lengthening of the health lifespan, and while some people will still develop dementia, a shortening of time in which people live with dementia. The discussion will focus on the risk factors, interventions, and economics of this, using evidence-based population-level as well as complex and individual interventions.
This knowledge offers hope, as it presents a large scope for individuals to reduce their risk of dementia. In addition, governments can decrease dementia in the population, helping individuals, families, and the economy.
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